Applied Clinical Informatics (ACI) is the Official eJournal of AMIA, IMIA, and EFMI. The journal aims to establish a platform that allows sharing of knowledge between clinical medicine and health IT specialists as well as bridging gaps between visionary design and successful and pragmatic deployment.

The target group of ACI is an international and potentially very influential readership, e.g.: chief information officers, chief executive officers, chief financial officers, chief clinical informatics officers, medical informatics researchers, nurse informaticians, consultants, public health officials, vendors, IT safety healthcare providers, informatics trainees, health information management and health informatics practitioners, as well as organizations such as AMIA, IMIA, EFMI, AMDIS, AHIMA, HIMSS or the equivalent.

The journal publishes Research articles, Reviews, Best practice papers, Letters to the editor, Case reports, Invited editorials and Brief scientific communications.

The core editorial subject matters of ACI are: clinical information systems (including electronic medical records and systems, personal health records, physician/provider order entry, electronic prescribing, clinical decision support, nursing information systems, patient scheduling and tracking tools, lab information systems, radiology information systems, PACS, GP information systems), administrative and management systems, eHealth systems, mobile health and quantified self applications, information technology development, deployment, and evaluation, socio-technical aspects of information technology and health IT training, accreditation, and certification.